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Likewise, in dose and application regimens as described before heparin (Belupo, Croatia), warfarin (Martefarin (Orion Pharma, Finland)), L-NAME (Sigma, USA) and L-arginine (Sigma, USA) dissolved in saline were used as well [1,14,15]

DOI: 10.1098/rsif.2019.0547

They are well known for their capacity to decrease inflammation and repair skin

The REDEFINE protocol escalated the dose over 16 weeks (0.25 0.5 1.0 1.7 2.4 mg), so the full pharmacologic dose was not reached until roughly week 17

DEFINITION 11 Research Use Only (RUO) A regulatory designation indicating a product is intended for laboratory research and not for human therapeutic, diagnostic, or veterinary application